diff --git a/comfy/model_management.py b/comfy/model_management.py
index 81c89b180..e7d327c74 100644
--- a/comfy/model_management.py
+++ b/comfy/model_management.py
@@ -1662,6 +1662,16 @@ def supports_nvfp4_compute(device=None):
 
     return True
 
+def supports_mxfp8_compute(device=None):
+    if not is_nvidia():
+        return False
+
+    props = torch.cuda.get_device_properties(device)
+    if props.major < 10:
+        return False
+
+    return True
+
 def extended_fp16_support():
     # TODO: check why some models work with fp16 on newer torch versions but not on older
     if torch_version_numeric < (2, 7):
diff --git a/comfy/ops.py b/comfy/ops.py
index 8c0aaec55..6306fd1be 100644
--- a/comfy/ops.py
+++ b/comfy/ops.py
@@ -966,16 +966,18 @@ def mixed_precision_ops(quant_config={}, compute_dtype=torch.bfloat16, full_prec
 def pick_operations(weight_dtype, compute_dtype, load_device=None, disable_fast_fp8=False, fp8_optimizations=False, model_config=None):
     fp8_compute = comfy.model_management.supports_fp8_compute(load_device) # TODO: if we support more ops this needs to be more granular
     nvfp4_compute = comfy.model_management.supports_nvfp4_compute(load_device)
+    mxfp8_compute = comfy.model_management.supports_mxfp8_compute(load_device)
 
     if model_config and hasattr(model_config, 'quant_config') and model_config.quant_config:
         logging.info("Using mixed precision operations")
         disabled = set()
         if not nvfp4_compute:
             disabled.add("nvfp4")
+        if not mxfp8_compute:
+            disabled.add("mxfp8")
         if not fp8_compute:
             disabled.add("float8_e4m3fn")
             disabled.add("float8_e5m2")
-            disabled.add("mxfp8")
         return mixed_precision_ops(model_config.quant_config, compute_dtype, disabled=disabled)
 
     if (